The present study aims at preparing an Emulgel formulation of Meloxicam using emulsifiers and various gelling agents along with the use of. PDF | Emulgel is one of the recent technologies in NDDS used for dual control release of emulsion and gel for topical use. The stability of. PDF | Topical therapies in cream, ointment, gel and lotion formulation, are an important component of dermatological therapeutic.
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Rheological studies revealed that the CHL emulgels exhibited a shear-thinning behavior with thixotropy. Preparation of an emulgel for treatment of aphthous ulcer on the basis of carbomers. Blackwell Scientific Publications; A study of shear and compression deformations on hydrophilic gels of tretinoin. National Center for Biotechnology InformationU.
The Pharmaceutical Press; Author information Article notes Copyright and License information Disclaimer. Swarbrick J, Boylan JC, editors. Received Formultaion 31; Accepted May Formulation and evaluation of topical preparations containing phenol and local vesicants.
Commercially available CHL topical powder was used for comparison.
Optimization of chlorphenesin emulgel formulation
Development of a thermoreversible gel for controlled-release ocular delivery of diclofenac sodium. Formulation and stability of chloramphenicol gel and emulgel. Fomrulation Complete Drug Reference. Medical Applications of Controlled Release. The Theory and Practice of Industrial Pharmacy.
Encyclopedia of Pharmaceutical Technology. They also exhibited higher drug release and antifungal activity than the CHL powder.
The influence of the type of the gelling agent and the concentration of both the oil phase and emulsifying agent on the drug release from the prepared emulgels was investigated using a 2 3 factorial design.
This article has been cited by other articles in PMC. Egypt J Pharm Sci. Analysis of data on the medicament release from ointments. The prepared emulgels were rmulgel for their physical appearance, rheological behavior, drug release, antifungal activity, and stability. As a general conclusion, it was suggested that the CHL emulgel formulation prepared with HPMC with the oil phase concentration in its low level and emulsifying agent concentration in its high level was the formula of choice since it showed the highest drug release and antifungal activity.
Marcel Dekker Inc; The drug release from all the emulgels was found to follow diffusion-controlled mechanism. This study was conducted to develop an emulgel formulation of chlorphenesin CHL using 2 types of gelling agents: Transdermal controlled release systems. It was found that the emulsifying agent concentration had the most pronounced effect on the drug release from the emulgels followed by the oil phase concentration and finally the type of the gelling agent.
Published online Sep 1.
Abstract This study was conducted to develop an emulgel formulation of chlorphenesin Formulaion using 2 types of gelling agents: Lea and Febiger; Bioavailability of salbutamol sulphate from different suppository formulations. Support Center Support Center. Stability studies showed that the physical appearance, rheological properties, drug release, and antifungal activity in all the prepared emulgels remained unchanged upon storage for 3 months.